Phathom Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of gastrointestinal (GI) diseases. With exclusive rights in the United States, Europe, and Canada to vonoprazan—a first-in-class potassium-competitive acid blocker (PCAB)—Phathom is working to transform the treatment of acid-related disorders.

Our current portfolio includes:

• VOQUEZNA® (vonoprazan) tablets, approved for the treatment of heartburn associated with Non-Erosive GERD, as well as the healing and maintenance of healing of Erosive GERD

• VOQUEZNA® TRIPLE PAK® (vonoprazan tablets, amoxicillin capsules, clarithromycin tablets) and VOQUEZNA® DUAL PAK® (vonoprazan tablets, amoxicillin capsules), approved for the treatment of H. pylori infection in adults

Beyond our commercialized products, we are advancing a pipeline focused on innovative treatments for other acid-related GI disorders, including Eosinophilic Esophagitis (EoE).

At Phathom, we are fueled by innovation, driven by purpose, and united by a shared commitment to improving patient outcomes. Our team comprises seasoned GI and industry experts with proven track records of delivering groundbreaking therapies, including anti-secretory agents. Together, we are tackling unmet medical needs and working hard to enhance the lives of patients.

We seek motivated, innovative problem-solvers who excel in fast-paced, collaborative environments and are eager to make an impact. At Phathom, you’ll find more than a career – you’ll join our “Phamily,” where employees feel empowered, valued, and inspired to do their best work.

In August 2025, we proudly earned the distinction of being Great Place to Work® certified, with 91% of surveyed employees affirming that Phathom is an exceptional workplace.

Ready to help change the landscape in GI? Join us and be part of something extraordinary.

The Senior Manager, Advanced Commercial Analytics, will lead the implementation and operational delivery of advanced analytics solutions across the commercial organization, including forecasting. This role is hands-on yet senior enough to provide methodological direction, coordinate cross-functional alignment, and ensure analytical outputs are delivered with rigor, consistency, and business relevance.

In addition to building and managing forecasting solutions, the Senior Manager will contribute to implementing predictive analytics supporting Next Best Action (NBA) capabilities, journey analytics, and optimization models. While the role includes strategic input and planning, the emphasis is firmly on applied execution, cross-functional delivery, and analytics implementation leadership.

ACCOUNTABILITIES

Forecasting Implementation

• Lead the hands-on development, enhancement, and deployment of forecasting models across brands and therapeutic areas.
• Translate business assumptions, market dynamics, and data inputs into reliable demand, patient, and revenue forecasts.
• Own forecasting methodology selection, model setup, calibration, validation, and documentation.
• Partner with Finance, Insights, Sales Operations, and Marketing to ensure forecasts align with business needs and planning cycles.
• Support ongoing forecast updates, scenario analyses, sensitivity testing, and long-range forecasting processes.

Omnichannel Journey Analytics

• Implement analytics that map HCP and consumer behaviors across personal promotion, non-personal promotion, digital marketing, and DTC.
• Build journey scoring models, engagement indicators, and behavioral insights to support brand and omnichannel activation.
• Provide practical guidance on how journey insights should inform next steps, segmentation, and communication strategies.

Next Best Action (NBA)

• Lead the design and implementation of NBA models and recommendation logic, working closely with digital and CRM teams.
• Translate business rules and modeling outputs into deployable NBA recommendations within CRM and digital platforms.
• Monitor NBA performance, measure lift, and refine algorithms and business rules based on real-world engagement data.
• Participate in shaping NBA strategy but focus primarily on execution and optimization of NBA capabilities.

Marketing Mix Analytics (MMA) & Optimization

• Contribute to developing, interpreting, and deploying MMA and promotional effectiveness models.
• Implement optimization routines and scenario tools that support brand planning and omnichannel investment decisions.
• Translate complex model outputs into practical, actionable recommendations for commercial teams.

Data Environment Utilization & Enhancement

• Use and contribute to the enhancement of the existing enterprise data ecosystem (Snowflake, AWS Redshift) to support forecasting and advanced analytics.
• Partner with data engineering to improve data quality, structure, and feature availability for modeling.
• Identify opportunities to streamline workflows, automate processes, and enhance data readiness for analytics.

Cross-Functional Execution

• Lead cross-functional teams in delivering analytics projects from definition through deployment.
• Act as a senior technical partner to Marketing, Digital, Insights, Sales Ops, and Finance.
• Provide practical, implementation-focused guidance to analysts and data scientists.
• Communicate analytical findings clearly and directly, focusing on what teams need to execute effectively.

Strategic Input

• Contribute to shaping the analytics roadmap for forecasting, NBA, and omnichannel analytics capabilities.
• Provide input on methodology, technology needs, and process improvements.
• Support leadership in identifying new opportunities to apply analytics to commercial challenges.

EDUCATION & EXPERIENCE

• At least 4 years of experience in commercial analytics, advanced analytics, omnichannel analytics, or digital marketing analytics in pharma/biotech or healthcare.
• Strong hands-on analytics skills with experience implementing advanced analytical models, segmentation, scoring, and journey analytics.
• Advanced technical skills to design, maintain, and refine pharmaceutical forecasting models with accuracy and consistency.
• Predictive modeling, segmentation, journey analytics, NLP, uplift modeling.
• NBA algorithms and rules-based systems.
• Expertise in Python, R, SQL, and visualization tools such as Power BI.
• Experience using and interpreting pharmaceutical datasets including IQVIA, Symphony, claims, CRM data, and digital marketing datasets.
• Demonstrated ability to translate analytical outputs into clear, actionable business recommendations.
• Strong communication skills and ability to work collaboratively across Marketing, Digital, Insights, Sales, and IT.
• Strong communication skills, with ability to translate analytics into operationally relevant insights.
• Experience mentoring analysts and supporting the development of junior team members.

Phathom’s Core Values:

• Perseverance – With hard work and determination, together we overcome all obstacles

• Humble – We put others first, remain grounded and let our work speak for itself

• Accountable – We are reliable and take personal responsibility in all that we do. We take pride and ownership in our work every day

• Transparent – We say what we mean, debate openly and respectfully, and have no hidden agendas

• Entrepreneurial – We are nimble, agile and embrace innovation. We challenge the status quo, enjoy change and approach problems unconventionally

Working at Phathom:

At Phathom, we prioritize the total well-being of our “Phamily” members. Our commitment is reflected in a competitive employee benefits package designed to support employees and their families’ overall well-being, now and in the future, including:

• Highly competitive medical, dental and vision coverage options with low monthly premiums

• Roth & Traditional 401(k) savings plan with annual employer match

• Long-term incentive equity compensation program

• Employee Stock Purchase Plan (ESPP)

• Comprehensive paid leave programs, including:

• 16 weeks of paid parental leave for all new parents

• 4-week part-time Bridge-Back-to-Work Program

• Hybrid and Flex Working Arrangements

• Unlimited Time Off

• 17 paid company holidays in addition to a year-end winter shutdown period

Other Benefits:

• Annual Fitness & Wellbeing Reimbursement

• Company-provided Life and Accidental Death & Dismemberment (AD&D) insurance

• Company-provided short and long-term disability benefits

• Company-funded HSA plan

• Accident and Hospital Indemnity insurance

• Employee Assistance Program (EAP)

• Employee recognition program

• Employee discounts

Annual Base Salary: $160,000-$190,000

Phathom is an equal opportunity employer that is committed to inclusion and diversity and provides equal opportunity for all applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, Veteran status, or other legally protected characteristics.

Applicants with a disability who require a reasonable accommodation for any part of the application, interview or hiring process can contact us by sending an email to?careers@phathompharma.com.